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Brightfield, Fluorescence & FISH Digital Pathology Scanner Aperio VERSA

Introduction：
The Aperio VERSA is a comprehensive digital pathology scanner, designed and developed to support the diverse imaging needs of cutting edge research facilities. The combination scanner is optimized for precision scanning of brightfield and fluorescent samples, with the accuracy and resolution required for FISH . From tissue-based and proteomic markers, to subcellular, molecular and in-situ hybridization probes, the Aperio VERSA delivers high-resolution, reliable imaging. Users can create a permanent record of their research – even faint fluorescent samples, which are often subject to fading. The Aperio VERSA is ideal for scanning multiplex slides at any magnification from 5x to 63x for the whole slide without the need for spectral imaging.

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High Capacity Digital Pathology Scanner Aperio GT450

Introduction：
Aperio GT 450 - Automated, High Capacity Digital Pathology Scanner with 3 New Features Integrating Innovation with Automation for the Research Laboratory At Leica Biosystems, we aim to enable researchers to accelerate their journey, transforming scientific exploration into translational outcomes. Our goal is to shape the future with novel technologies that inspire every researcher’s exploration of biology. The Aperio GT 450 is proven scanning technology that consists of three upgrades that improve image quality and flexible scanning solutions in research settings: Z-Stack Scanning, Automatic Narrow Stripe, and 20x Magnification. Z-Stack Scanning Multiplane scanning that produces a composite, 3D image that enables research pathologists to review slide samples at varied levels of thickness, similar to a traditional microscope. Automatic Narrow Stripe Scanning Quality control that enables an automatic rescan of a slide when the system detects image quality issues resulting from a tilted slide or tilted tissue. Allows users to save time in their workflow by not re-preparing or readjusting slides, thus reducing labor hours. 20x Magnification In addition to 40x magnification, operators will have the option to scan slides at 20x magnification – our solution to saving space.

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Digital Pathology Scanner Aperio CT 6

Introduction：
The Aperio CT 6 features excellent imaging performance and user-friendly functional design, which utilizes less slide movement and operation to improve the efficiency of scanning and image reading, while providing superior image quality as you expect. Its full-field digital slices are widely used in scientific research, education, drug safety evaluation, forensic pathology, and other fields. I. High-Quality Image Quality Accumulated over 150 years of optical technology; the prism camera truly restores tissue colors; adopts high-fidelity color restoration technology to enhance sensitivity to red colors and precisely restore color details of H&E slices. II. Multiple Brightfield Slice Scanning Supports four types of brightfield slice scanning; developed specialized algorithms for special slices like light-colored ones; supports scanning of more sizes of slices, allowing quick switching to large slide scanning mode; for tissues with uneven thickness, it can perform multi-layer scanning and fusion imaging. III. Efficient Workflow Leica Aperio line-scan technology for fast imaging and improved efficiency; automatic mode and manual mode can be switched freely; Leica's comprehensive solution for scanning imaging, image reading, management, and analysis.

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Automatic karyotype scanning analyzer CytoVision CX

Introduction：
     CytoVision is the one image analysis and management system that provides Cytogenetic laboratories with an integrated, scalable platform for brightfield and fluorescent samples, because only Leica combines the expertise in image analysis, robotics and microscopy needed to deliver and support a truly integrated cytogenetics platform. A scalable, modular approach to the design and development of the CytoVision platform ensures a future-proof solution for any laboratory – from configurations to support a single application workstation through to fully-networked, multi-application nationwide programs.

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Automatic karyotype scanning analyzer CytoVision GSL 120

Introduction：
      CytoVision is the one image analysis and management system that provides Cytogenetic laboratories with an integrated, scalable platform for brightfield and fluorescent samples, because only Leica combines the expertise in image analysis, robotics and microscopy needed to deliver and support a truly integrated cytogenetics platform. A scalable, modular approach to the design and development of the CytoVision platform ensures a future-proof solution for any laboratory – from configurations to support a single application workstation through to fully-networked, multi-application nationwide programs.   I. Automatic Target Cell Detection, Accurate and Efficient Leica's exclusive classifier can automatically identify target cells. It prioritizes the identified cells based on their overlapping degree, nuclear size, and the distance between dual nuclei, and selects cells with better results for photographing. The cell database can automatically incorporate customers' images for training, achieving increasing accuracy through continued use. II. Effortless Micronucleus Analysis, Flexible Mutation Analysis, Convenient and Quick Classification: Lymphocytes are classified based on the number of micronuclei. Statistics: Counting the number of cells in each category, the number of micronucleated cells, micronucleated cell rate, micronucleus rate, and lymphocyte conversion rate. Analysis: Chromosome number and structural abnormalities (such as double-attached, non-attached microbodies, fragments, centromeric rings, reciprocal translocations, etc.). III. Fully Automated, Unattended Scanning Imaging Auto-focusing, automatic switching of objectives, and automatic switching of filter cubes. 1.25X objective lens automatically identifies tissue etching areas or cellular regions. Automatic scanning and capturing of fluorescent signal-bearing cells. High-throughput capacity of 120 slides, meeting clinical and laboratory needs. IV. Z-Stack Layer Scanning, Multi-Layer Capture, Complete Signal Easily capturing multi-focal plane and multi-fluorescence channel images with large depth of field. The full-information image covers all information within the entire slice thickness. V. High-Definition Imaging, Clear Display of Fluorescent Signals 1-inch CCD and research-grade microscope capture high-resolution fluorescent images. Images under combined fluorescence are restored to true signals under the microscope. The fluorescent dot counting function can automatically report the number and status of fluorescent dots, as well as perform automatic Z-axis image acquisition for interphase and metaphase FISH fluorescent signals.

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Automatic karyotype scanning analyzer CytoVision GSL 10

Introduction：
CytoVision is the one image analysis and management system that provides Cytogenetic laboratories with an integrated, scalable platform for brightfield and fluorescent samples, because only Leica combines the expertise in image analysis, robotics and microscopy needed to deliver and support a truly integrated cytogenetics platform. A scalable, modular approach to the design and development of the CytoVision platform ensures a future-proof solution for any laboratory – from configurations to support a single application workstation through to fully-networked, multi-application nationwide programs. I. Automatic Target Cell Detection, Accurate and Efficient Leica's exclusive classifier can automatically identify target cells. It prioritizes the identified cells based on their overlapping degree, nuclear size, and the distance between dual nuclei, and selects cells with better results for photographing. The cell database can automatically incorporate customers' images for training, achieving increasing accuracy through continued use. II. Effortless Micronucleus Analysis, Flexible Mutation Analysis, Convenient and Quick Classification: Lymphocytes are classified based on the number of micronuclei. Statistics: Counting the number of cells in each category, the number of micronucleated cells, micronucleated cell rate, micronucleus rate, and lymphocyte conversion rate. Analysis: Chromosome number and structural abnormalities (such as double-attached, non-attached microbodies, fragments, centromeric rings, reciprocal translocations, etc.). III. Fully Automated, Unattended Scanning Imaging Auto-focusing, automatic switching of objectives, and automatic switching of filter cubes. 1.25X objective lens automatically identifies tissue etching areas or cellular regions. Automatic scanning and capturing of fluorescent signal-bearing cells. IV. Z-Stack Layer Scanning, Multi-Layer Capture, Complete Signal Easily capturing multi-focal plane and multi-fluorescence channel images with large depth of field. The full-information image covers all information within the entire slice thickness. V. High-Definition Imaging, Clear Display of Fluorescent Signals 1-inch CCD and research-grade microscope capture high-resolution fluorescent images. Images under combined fluorescence are restored to true signals under the microscope. The fluorescent dot counting function can automatically report the number and status of fluorescent dots, as well as perform automatic Z-axis image acquisition for interphase and metaphase FISH fluorescent signals.

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