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Optical Tweezers – Fluorescence & Label-free Microscopy C-Trap G2

DNA–binding proteins

Protein folding

Cytoskeletal structure and transport

Phase separation

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Characteristics

Mechanical resolution

<0.1 pN at 100 Hz (1 μ m beads at 0.3 pN/nm trap stiffness)

Maximum escape force

>1000 pN using 4.5 μ m polystyrene beads

Mechanical stability

<0.3 pN over 2 minutes

Distance resolution of optical trap

<3 A at 100 Hz

Minimum step

2 nm

Tracking accuracy of sports microspheres

<3 nm at 100 Hz using video analysis, simultaneous with force and fluorescence detection

Moving range (FoM)

15 Khz

Optical trap type

Continuous wave for unparalleled stickiness, stability and precision

Description

The C-Trap® provides the world’s first dynamic single-molecule microscope to allow simultaneous manipulation and visualization of single-molecule interactions in real time.

It combines high-resolution optical tweezers, fluorescence, and label-free microscopy, and an advanced microfluidics system in a truly integrated and correlated solution.

 

How does it work?

In 2018 Arthur Ashkin won the Nobel Prize in Physics for his discovery that the momentum of light can be used as an incredibly sensitive set of “tweezers”.

By shooting a laser through a microscope, he created a highly focused beam of light strong enough to trap and hold in place objects such as plastic beads. These beads can be coated to stick to a variety of biomolecules, such as proteins, cytoskeleton filaments, DNA, or RNA. Furthermore, the tiniest forces applied to these molecules can be measured as well, giving the world access to a tool not only capable of manipulating biomolecules but also capable of detecting what’s happening to them.

 

How can it be applied to my research?

Whether you are aiming to make novel discoveries in the life sciences or develop successful drug candidates, we work on a personal level to find the right solution for you. Browse our extended list of applications to discover how these technologies can benefit your research.

 

-Stable and precise sample manipulation

Different optical tweezers configurations and advanced manipulation features allow you to get the most out of your sample.

 

-A wide variety of visualization capabilities

Choose and combine from a variety of imaging methods designed specifically to solve the needs of different experimental designs.

 

-Introducing the new C-Trap products
Dymo & Edge

With the desire to constantly produce breakthrough discoveries, you need an easy-to-use instrument, fully-optimized for your applications that should bring unprecedented insights with high precision, accuracy, and reliability, in short time. Discover your solutions below!

 

-High throughput experiment workflow

Loading your sample and analysing your data in less than 30 minutes.

 

-Easy and intuitive software package

Check how you can completely automate your experiments using our user-centered software workflow, experience seamless process from data collection to data analysis.

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